ELOVL6-IN-5
ELOVL6-IN-5 (compound B) is an inhibitor of the elongase enzyme of long-chain fatty acid family 6 (ELOVL6) . ELOVL6 is a rate-limiting enzyme for the elongation of saturated and monounsaturated long-chain fatty acids and is an effective target for inhibiting diabetes. ELOVL6-IN-5 reduces hepatic fatty acid levels in a mouse model of diet-induced obesity (DIO) . However, ELOVL6 inhibition by ELOVL6-IN-5 did not improve insulin resistance[1].
Product Specifications
CAS Number
1135000-36-0
UNSPSC
12352005
Target
ELOVL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/elovl6-in-5.html
Purity
95.12
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N1C2CCC1CC(S(=O)(C3=NC=CC=C3)=O)C2)NC4=CC=C(C(F)(F)F)C=C4
Molecular Formula
C20H20F3N3O3S
Molecular Weight
439.45
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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