(24E) -3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid
Selected Variant
HY-N1783
Size: 1 mg
(24E) -3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid is a potent PTP1B inhibitor, with an IC50 of 0.4 μM. (24E) -3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid exhibits potent PTP1B inhibitory activity without cytotoxicity[1].
Product Specifications
CAS Number
329975-47-5
UNSPSC
12352211
Target
Phosphatase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/24e-3-4-secocucurbita-4-24-diene-3-26-29-trioic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CC[C@@H]([C@@]1(C)[C@]2([H])[C@]3(C)CC[C@@]([C@H](C)CC/C=C(C(O)=O)\C)(C)[C@@]3(C)CC1)/C(CC2)=C(C(O)=O)\C
Molecular Formula
C31H48O6
Molecular Weight
516.71
References & Citations
[1]Maarisit W, et al. Protein tyrosine phosphatase 1B inhibitory properties of seco-cucurbitane triterpenes obtained from fruiting bodies of Russula lepida. J Nat Med. 2017 Jan;71 (1) :334-337.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Gp83 Mouse Monoclonal Antibody [4D1]](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea814c7/imageurl/em1701-53.webp)
BNC472216-100 1x 100 µL
CD50 / ICAM3 (CG106), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC942635-100 1x 100 µL
Gastrin (GAST/2635), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470102-100 1x 100 µL
Golgi Complex (371-4), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880838-500 1x 500 µL
MAGE A1 (MZ2E/838), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 