(24E) -3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid
Selected Variant
HY-N1783
Size: 1 mg
(24E) -3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid is a potent PTP1B inhibitor, with an IC50 of 0.4 μM. (24E) -3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid exhibits potent PTP1B inhibitory activity without cytotoxicity[1].
Product Specifications
CAS Number
329975-47-5
UNSPSC
12352211
Target
Phosphatase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/24e-3-4-secocucurbita-4-24-diene-3-26-29-trioic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CC[C@@H]([C@@]1(C)[C@]2([H])[C@]3(C)CC[C@@]([C@H](C)CC/C=C(C(O)=O)\C)(C)[C@@]3(C)CC1)/C(CC2)=C(C(O)=O)\C
Molecular Formula
C31H48O6
Molecular Weight
516.71
References & Citations
[1]Maarisit W, et al. Protein tyrosine phosphatase 1B inhibitory properties of seco-cucurbitane triterpenes obtained from fruiting bodies of Russula lepida. J Nat Med. 2017 Jan;71 (1) :334-337.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PA2105-HRP 100 µg/Vial
Anti-Cystatin A/CSTA Antibody Picoband®, HRP Conjugate
Sign In for Pricing
View Details 
A06347-iFluor647 100 µg
Anti-RND1 Antibody Picoband® (iFluor647 Conjugate)
Sign In for Pricing
View Details 
PB9553-Dylight488 100 µg
Anti-EBAG9 Antibody Picoband® (Dylight488 Conjugate)
Sign In for Pricing
View Details 
BNC471964-500 1x 500 µL
NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) (NGFR/1964), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
PB9231-Cy3 100 µg/Vial
Anti-KLF6 Antibody Picoband® (Cy3 Conjugate)
Sign In for Pricing
View Details 