DDR1-IN-1

DDR1-IN-1 is a potent and selective DDR1 receptor tyrosine kinase inhibitor with an IC50 of 105 nM; 4-fold less potent for DDR2 (IC50 = 413 nM)[1].

Discoidin Domain Receptor

Reference compound

Protein Tyrosine Kinase/RTK

Cancer-Kinase/protease

Cancer

https://www.medchemexpress.com/DDR1-IN-1.html

DMSO : 100 mg/mL (ultrasonic)

O=C(NC1=CC=C(C)C(OC2=CC3=C(NC(C3)=O)C=C2)=C1)C4=CC=C(CN5CCN(CC)CC5)C(C(F)(F)F)=C4

552.59

[1]Kim HG, et al. Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor. ACS Chem Biol. 2013 Oct 18;8(10):2145-50.

Room Temperature

http://file.medchemexpress.com/batch_PDF/HY-13979/DDR1-IN-1-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-13979/DDR1-IN-1-SDS-MedChemExpress.pdf

No Development Reported

1449685-96-4