PF-05387252
PF-05387252 is a potent and selective IRAK4 inhibitor with the activity of inhibiting endogenous TLR signaling pathways. PF-05387252 has shown anti-inflammatory activity in experimental models and may have potential clinical application value in inhibiting psoriasis. Although PF-05387252 and its related compounds have shown anti-inflammatory effects in animal models, their efficacy in inhibiting psoriasis has not yet been verified[1].
Product Specifications
CAS Number
1604034-71-0
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pf-05387252.html
Smiles
N#CC1=CC2=C(C=C1)C3=C(C4=CC(OC)=C(C=C4N=C3)OCCCN5CCN(CC5)C)N2
Molecular Formula
C25H27N5O2
Molecular Weight
429.51
References & Citations
[1]Natural Modulators of Endosomal Toll-Like Receptor-Mediated Psoriatic Skin Inflammation
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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