Nystose

Nystose is a tetrasaccharide with two fructose molecules linked via beta (1→2) bonds to the fructosyl moiety of sucrose. Nystose exhibits prebiotic, immunomodulatory, and metabolism regulating activities. Nystose promotes the bone mineralization by activating the Wnt/β-catenin signaling pathway[2].

Product Specifications

CAS Number

[13133-07-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; TGF-beta/Smad; Wnt; β-catenin

Type

Natural Products

Related Pathways

Anti-infection; Stem Cell/Wnt; TGF-beta/Smad

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Infection; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Nystose.html

Purity

99.90

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 83.33 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@@](CO[C@@]2(O[C@H](CO)[C@@H](O)[C@@H]2O)CO[C@@]3(O[C@H](CO)[C@@H](O)[C@@H]3O)CO)(O[C@H](CO)[C@H]1O)O[C@H]([C@@H]([C@@H](O)[C@@H]4O)O)O[C@@H]4CO

Molecular Formula

C24H42O21

Molecular Weight

666.58

Precautions

H302, H315, H319, H335

References & Citations

[1]Ziesenitz SC, et al. In vitro assessment of nystose as a sugar substitute. J Nutr. 1987 May;117 (5) :846-51.|[2]N Yoshida, et al., Effects of 1-kestose and nystose on the intestinal microorganisms and immune system in mice[J]. Journal of applied Glycoscience, 2006, 53 (3) : 175-180.|[3]Zhang Q, et al. Nystose attenuates bone loss and promotes BMSCs differentiation to osteoblasts through BMP and Wnt/β-catenin pathway in ovariectomized mice[J]. Food Science and Human Wellness, 2023, 12 (2) : 634-646.