Formoterol (hemifumarate hydrate)

Formoterol hemifumarate hydrate is a selective, long-acting beta 2-adrenoceptor agonist. Formoterol is a bronchodilator used for the research of the asthma and chronic obstructive pulmonary disease (COPD) . Formoterol hemifumarate hydrate induces mitochondrial biogenesis and promotes cognitive recovery after traumatic brain injury[1][2][3].

Product Specifications

CAS Number

[183814-30-4]

UNSPSC

12352005

Hazard Statement

H301

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/formoterol-hemifumarate-hydrate.html

Purity

99.91

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC(/C=C/C(O)=O)=O.COC(C=C1)=CC=C1C[C@H](C)NC[C@H](C2=CC(NC=O)=C(C=C2)O)O.O.[1/2]

Molecular Formula

C19H24N2O4.1/2C4H4O4.H2O

Molecular Weight

840.91

Precautions

H301

References & Citations

[1]Bartow RA, et al. An update of its pharmacological properties and therapeutic efficacy in the management of asthma [published correction appears in Drugs 1998 Apr;55 (4) :517]. Drugs. 1998;55 (2) :303-322. |[2]Tashkin DP. Formoterol for the Treatment of Chronic Obstructive Pulmonary Disease. Int J Chron Obstruct Pulmon Dis. 2020;15:3105-3122. Published 2020 Nov 27.|[3]Vekaria HJ, et al. Formoterol, a β2-adrenoreceptor agonist, induces mitochondrial biogenesis and promotes cognitive recovery after traumatic brain injury. Neurobiol Dis. 2020;140:104866.