DCAF1 binder 1
DCAF1 binder 1 is a selective for the CRL4 DCAF1 E3 ligase complex. DCAF1 binder 1 is a ligands for E3 Ligase, involving in targeted protein degradation (TPD) [1].
Product Specifications
CAS Number
3053860-67-3
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dcaf1-binder-1.html
Purity
99.12
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
NCCNC1=NC(C2(C3=CC=C(C=C3)Cl)CCCCC2)=NC4=C1C=CC(N5CCN(CC5)C(C)=O)=C4
Molecular Formula
C28H35ClN6O
Molecular Weight
507.07
References & Citations
[1]Schroeder M, et al. Reinstating targeted protein degradation with DCAF1 PROTACs in CRBN PROTAC resistant settings[J]. bioRxiv, 2023: 2023.04. 09.536153.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![PE Anti-Human HLA-DP Antibody[B7/21]](https://cdn.genprice.uk/products/763/68dd14ad061270361e7d321e/imageurl08/an00566d.webp)
![(3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone](https://cdn.genprice.uk/products/572/6214513493982/imageurl/trc-b671500-25mg.webp)
TRC-B671500-25MG 25 mg
(3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone
Sign In for Pricing
View Details ![RRM1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1F9]](https://cdn.genprice.uk/products/937/6868c3bc994c49e6dc3fdb95/imageurl/ta804454am.webp)
TA804454AM 100 µL
RRM1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1F9]
Sign In for Pricing
View Details 