Phenanthrene

Phenanthrene is an orally active polycyclic aromatic hydrocarbon (PAH) that induces inflammation, oxidative stress, and apoptosis. Additionally, phenanthrene is commonly used to detect or assess PAH pollution in the environment[1][2][3][4].

Product Specifications

CAS Number

[85-01-8]

UNSPSC

12352005

Hazard Statement

H302, H410

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/phenanthrene.html

Purity

99.82

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

C12=CC=CC=C1C=CC3=CC=CC=C23

Molecular Formula

C14H10

Molecular Weight

178.23

Precautions

H302, H410

References & Citations

[1]Sun K, et al. Subcellular distribution and biotransformation of phenanthrene in pakchoi after inoculation with endophytic Pseudomonas sp. as probed using HRMS coupled with isotope-labeling. Environ Pollut. 2018 Jun;237:858-867.|[2]Dupuy J, et al. Effect and localization of phenanthrene in maize roots. Chemosphere. 2016 Apr;149:130-6.|[3]Ma H, et al. Effects of phenanthrene on oxidative stress and inflammation in lung and liver of female rats. Environ Toxicol. 2020 Jan;35 (1) :37-46.|[4]Hong X, et al. Phenanthrene-Induced Apoptosis and Its Underlying Mechanism. Environ Sci Technol. 2017 Dec 19;51 (24) :14397-14405.