Mn007
Mn007 is a potent inhibitor of bovine pancreatic DNase I, with the IC50 of 45 μM, by forming molecular aggregation. Mn007 shows suppression of S. pyogenes growth in human whole blood[1].
Product Specifications
CAS Number
[1843236-92-9]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mn007.html
Purity
90.0
Solubility
10 mM in DMSO
Smiles
NC1=CC(N=C(N2CCN(C(CC)C3=NN=NN3CC4=CC=CS4)CC2)S5)=C5C(F)=C1
Molecular Formula
C20H23FN8S2
Molecular Weight
458.58
References & Citations
[1]Kenta Morita, et al. Molecular Aggregation Strategy for Inhibiting Dnases. JACS Au 2024, April 16.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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