Cinchonine (monohydrochloride hydrate)
Cinchonine ((8R,9S) -Cinchonine) monohydrochloride hydrate is a natural compound which has been effectively used as antimalarial agent. Cinchonine monohydrochloride hydrate activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Cinchonine monohydrochloride hydrate is also an inhibitor of human platelet aggregation. Cinchonine monohydrochloride hydrate possesses a suppressive effect on adipogenesis[1].
Product Specifications
Product Name Alternative
(8R,9S) -Cinchonine (monohydrochloride hydrate) ; LA40221 (monohydrochloride hydrate)
UNSPSC
12352005
Hazard Statement
H302+H312+H332
Target
Apoptosis; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Infection; Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cinchonine-monohydrochloride-hydrate.html
Solubility
10 mM in DMSO
Smiles
O[C@@H](C1=CC=NC2=CC=CC=C12)[C@]3([H])[N@@]4C[C@H](C=C)[C@@H](CC4)C3.[H]Cl.[x].O
Molecular Formula
C19H22N2O.HCl.xH2O
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-Y0152A/Cinchonine-monohydrochloride-hydrate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-Y0152A/
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Plasmodium
CAS Number
[206986-88-1]
Available Sizes
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