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Cav 2.2 blocker 2

Cav 2.2 blocker 2 is a Cav2.2 calcium channel blocker extracted from patent WO2017046581A1, compound 1. Cav 2.2 blocker 2 can reverses hyperalgesia associated with an injury or inflammation in conjunction with the opioid[1].

Product Specifications

CAS Number

[1204535-44-3]

UNSPSC

12352005

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cav-2-2-blocker-2.html

Purity

98.51

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=CN=C1C)N2[C@@H](C)CN(S(=O)(C3=CC=C(C(F)(F)F)C=C3)=O)CC2

Molecular Formula

C19H20F3N3O3S

Molecular Weight

427.44

References & Citations

[1]Ali Z, et, al. Composition comprising cav2.2 calcium channel blocker and opioid. WO2017046581A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

N-type calcium channel

Available Sizes

Curated Selection

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