Recombinant Human Matrix Gla protein (MGP)

Product Specifications

Product Name Alternative

Cell growth-inhibiting gene 36 protein

Abbreviation

Recombinant Human MGP protein

Gene Name

MGP

UniProt

P08493

Expression Region

20-96aa

Organism

Homo sapiens (Human)

Target Sequence

YESHESMESYELNPFINRRNANTFISPQQRWRAKVQERIRERSKPVHELNREACDDYRLCERYAMVYGYNAAYNRYF

Tag

N-terminal 10xHis-tagged and C-terminal Myc-tagged

Type

In Stock Protein

Source

E.coli

Field of Research

Signal Transduction

Relevance

Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.

Endotoxin

Not test

Purity

Greater than 90% as determined by SDS-PAGE.

Activity

Not Test

Form

Liquid or Lyophilized powder

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Function

Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.

Molecular Weight

14.5 kDa

References & Citations

"Overexpression of matrix Gla protein mRNA in malignant human breast cells: isolation by differential cDNA hybridization." Chen L., O'Bryan J.P., Smith H.S., Liu E. Oncogene 5:1391-1395 (1990)

Storage Conditions

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.