4 (3H) -Quinazolinone
4 (3H) -quinazolinone is a fused nitrogen heterocyclic compound whose derivatives have a wide range of antimicrobial and antitumor activities[1][2].
Product Specifications
CAS Number
491-36-1
UNSPSC
12352005
Hazard Statement
H302
Target
Bacterial; EGFR
Type
Natural Products
Related Pathways
Anti-infection; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection; Endocrinology; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/4_3H_-Quinazolinone.html
Purity
99.91
Solubility
DMSO : ≥ 100 mg/mL|H2O : 1.2 mg/mL (ultrasonic)
Smiles
O=C1NC=NC2=C1C=CC=C2
Molecular Formula
C8H6N2O
Molecular Weight
146.15
Precautions
H302
References & Citations
[1]Qian Y, et al. Exploration of the Structural Space in 4 (3H) -Quinazolinone Antibacterials[J]. J Med Chem. 2020 May 28;63 (10) :5287-5296.|[2]Gatadi S, et al. 4 (3H) -Quinazolinone derivatives: Promising antibacterial drug leads. Eur J Med Chem. 2019 May 15;170:157-172.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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