4 (3H) -Quinazolinone

4 (3H) -quinazolinone is a fused nitrogen heterocyclic compound whose derivatives have a wide range of antimicrobial and antitumor activities[1][2].

Product Specifications

CAS Number

[491-36-1]

UNSPSC

12352005

Hazard Statement

H302

Target

Bacterial; EGFR

Type

Natural Products

Related Pathways

Anti-infection; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection; Endocrinology; Metabolic Disease; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/4_3H_-Quinazolinone.html

Purity

99.91

Solubility

DMSO : ≥ 100 mg/mL|H2O : 1.2 mg/mL (ultrasonic)

Smiles

O=C1NC=NC2=C1C=CC=C2

Molecular Formula

C8H6N2O

Molecular Weight

146.15

Precautions

H302

References & Citations

[1]Qian Y, et al. Exploration of the Structural Space in 4 (3H) -Quinazolinone Antibacterials[J]. J Med Chem. 2020 May 28;63 (10) :5287-5296.|[2]Gatadi S, et al. 4 (3H) -Quinazolinone derivatives: Promising antibacterial drug leads. Eur J Med Chem. 2019 May 15;170:157-172.