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QD394

Product Specifications

UNSPSC Description

QD394 is a reactive oxygen species (ROS) inducer that can induce lipid peroxidation, increase intracellular ROS accumulation, inhibit STAT3 phosphorylation, and induce ferroptosis[1].

Target Antigen

Reactive Oxygen Species

Type

Reference compound

Related Pathways

Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/qd394.html

Smiles

O=C1C=C(C(C2=C1N=CN=C2)=O)NC3=CC=C(N4CCN(CC4)C)C=C3

Molecular Weight

349.39

References & Citations

[1]Shuai Hu, et al. A Novel Redox Modulator Induces a GPX4-Mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species. J Med Chem. 2020 Sep 10;63(17):9838-9855.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-139369/QD394-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-139369/QD394-SDS-MedChemExpress.pdf

CAS Number

2132411-21-1

Available Sizes

Curated Selection

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