QD394
QD394 is a reactive oxygen species (ROS) inducer that can induce lipid peroxidation, increase intracellular ROS accumulation, inhibit STAT3 phosphorylation, and induce ferroptosis[1].
Product Specifications
CAS Number
[2132411-21-1]
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/qd394.html
Purity
99.0
Solubility
DMSO : 7.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C=C(C(C2=C1N=CN=C2)=O)NC3=CC=C(N4CCN(CC4)C)C=C3
Molecular Formula
C19H19N5O2
Molecular Weight
349.39
References & Citations
[1]Shuai Hu, et al. A Novel Redox Modulator Induces a GPX4-Mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species. J Med Chem. 2020 Sep 10;63 (17) :9838-9855.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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