QD394
QD394 is a reactive oxygen species (ROS) inducer that can induce lipid peroxidation, increase intracellular ROS accumulation, inhibit STAT3 phosphorylation, and induce ferroptosis[1].
Product Specifications
CAS Number
[2132411-21-1]
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/qd394.html
Purity
99.0
Solubility
DMSO : 7.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C=C(C(C2=C1N=CN=C2)=O)NC3=CC=C(N4CCN(CC4)C)C=C3
Molecular Formula
C19H19N5O2
Molecular Weight
349.39
References & Citations
[1]Shuai Hu, et al. A Novel Redox Modulator Induces a GPX4-Mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species. J Med Chem. 2020 Sep 10;63 (17) :9838-9855.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
207758-ML550 100 µL
KSR2 (Kinase Suppressor of Ras 2, Kinase Suppressor of Ras-2, FLJ25965) (MaxLight 550)
Ask
View Details 123140-ML490 100 µL
AKAP7 (A-kinase Anchor Protein 7 Isoforms alpha and beta, AKAP-7 Isoforms alpha and beta, Protein Kinase A-anchoring Protein 7 Isoforms alpha/beta, A-kinase Anchor Protein 18kD, AKAP 18, AKAP18) (MaxLight 490)
Ask
View Details 
MBS9427535-02 5x 96 Tests
Mouse Polymerase I and transcript release factor ELISA Kit
Ask
View Details 