QD394

QD394 is a reactive oxygen species (ROS) inducer that can induce lipid peroxidation, increase intracellular ROS accumulation, inhibit STAT3 phosphorylation, and induce ferroptosis[1].

Product Specifications

CAS Number

[2132411-21-1]

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/qd394.html

Purity

99.0

Solubility

DMSO : 7.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C=C(C(C2=C1N=CN=C2)=O)NC3=CC=C(N4CCN(CC4)C)C=C3

Molecular Formula

C19H19N5O2

Molecular Weight

349.39

References & Citations

[1]Shuai Hu, et al. A Novel Redox Modulator Induces a GPX4-Mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species. J Med Chem. 2020 Sep 10;63 (17) :9838-9855.