Recombinant Dog Calcitonin (CALCA), partial

Product Specifications

Product Name Alternative

CALCA; CALC; CCALCI; Calcitonin

Abbreviation

Recombinant Dog CALCA protein, partial

Gene Name

CALCA

UniProt

P41547

Expression Region

85-116aa

Organism

Canis lupus familiaris (Dog) (Canis familiaris)

Target Sequence

CSNLSTCVLGTYSKDLNNFHTFSGIGFGAETP

Tag

N-terminal 6xHis-SUMO-tagged

Type

Developed Protein

Source

E.coli

Field of Research

Cardiovascular

Relevance

Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

Endotoxin

Not test

Purity

Greater than 90% as determined by SDS-PAGE.

Activity

Not Test

Form

Liquid or Lyophilized powder

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Function

Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

Molecular Weight

19.4 kDa

References & Citations

"Molecular analysis and chromosomal assignment of the canine CALC-I/alpha-CGRP gene."Wende S., Krempler A., Breen M., Brunnberg L., Brenig B.Mamm. Genome 11:736-740 (2000)

Storage Conditions

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.