CYM51010

CYM51010 is a biased ligand of μ-opioid receptor – δ-opioid receptor heterodimers with an EC50 of 403 nM. CYM51010 exhibits anti-nociceptive activity similar to morphine but with a decreased levels of tolerance development and withdrawal symptoms[1].

Product Specifications

CAS Number

[1069498-96-9]

UNSPSC

12352005

Hazard Statement

H302

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cym51010.html

Purity

99.12

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1(CCC2=CC=CC=C2)CCN(CC3=CC=C(NC(C)=O)C=C3)CC1)OCC

Molecular Formula

C25H32N2O3

Molecular Weight

408.53

Precautions

H302

References & Citations

[1]Pinello C, et al. Characterization of an agonist probe for opioid receptor mu 1 (OPRM1) -opioid receptor delta 1 (OPRD1) heterodimerization. 2012 Dec 17 [updated 2013 Apr 5]. In: Probe Reports from the NIH Molecular Libraries Program [Internet].