Bax activator-1
Bax activator-1 (compound 106) is a Bax activator that induces Bax-dependent tumor cell apoptosis[1].
Product Specifications
CAS Number
[1638526-94-9]
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bax-activator-1.html
Purity
98.45
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(C1=NN(CC2=CC=CC(OC)=C2)C3=C1CN(CC4=CC=C(C)C(C)=C4)CC3)N5C[C@H](O)CCC5
Molecular Formula
C29H36N4O3
Molecular Weight
488.62
References & Citations
[1]Zhao G, et al. Activation of the proapoptotic Bcl-2 protein Bax by a small molecule induces tumor cell apoptosis. Mol Cell Biol. 2014 Apr;34 (7) :1198-207.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bax
Available Sizes
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