Bax activator-1

Bax activator-1 (compound 106) is a Bax activator that induces Bax-dependent tumor cell apoptosis[1].

Product Specifications

CAS Number

[1638526-94-9]

UNSPSC

12352005

Target

Apoptosis; Bcl-2 Family

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bax-activator-1.html

Purity

98.45

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(C1=NN(CC2=CC=CC(OC)=C2)C3=C1CN(CC4=CC=C(C)C(C)=C4)CC3)N5C[C@H](O)CCC5

Molecular Formula

C29H36N4O3

Molecular Weight

488.62

References & Citations

[1]Zhao G, et al. Activation of the proapoptotic Bcl-2 protein Bax by a small molecule induces tumor cell apoptosis. Mol Cell Biol. 2014 Apr;34 (7) :1198-207.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Bax

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

48023061 1.0 µg DNA

TRNAF14P Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

Ask

View Details

sc-270501-V 200 µL

USF-1 shRNA (r) Lentiviral Particles

Ask

View Details

NBP3-14123AF350 0.1 mL

Mouse Monoclonal MLH1 Antibody (MLH1/6710) [Alexa Fluor 350]

Ask

View Details

MF-0034298-01 25 mg

VER-00158411

Ask

View Details

MF-0034298-02 50 mg

VER-00158411

Ask

View Details

MF-0034298-03 100 mg

VER-00158411

Ask

View Details