Salicyl-AMS
Salicyl-AMS is a mycobactin biosynthesis inhibitor which can also inhibit M. tuberculosis growth in vitro under iron-limited conditions.
Product Specifications
CAS Number
863238-55-5
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/TRPM2_agonist-1.html
Purity
99.59
Solubility
DMSO : ≥ 90.5 mg/mL
Smiles
O[C@@H]1[C@@H](COS(=O)(NC(C2=C(O)C=CC=C2)=O)=O)O[C@@H](N3C(N=CN=C4N)=C4N=C3)[C@@H]1O
Molecular Formula
C17H18N6O8S
Molecular Weight
466.43
References & Citations
[1]Lun S, et al. Pharmacokinetic and in vivo efficacy studies of the mycobactin biosynthesis inhibitor salicyl-AMS in mice. Antimicrob Agents Chemother. 2013 Oct;57 (10) :5138-40.|[2]Ferreras JA, et al. Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis. Nat Chem Biol. 2005 Jun;1 (1) :29-32.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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