H3R antagonist 1 (hydrochloride)
H3R antagonist 1 hydrochloride is a histamine receptor 3 (H3R) inverse agonist. H3R antagonist 1 hydrochloride increases the expression levels of myelin-associated glycoprotein (MAG) and myeline basic protein (MBP) in differentiating oligodendrocytes. H3R antagonist 1 hydrochloride can be used for the study of multiple sclerosis[1].
Product Specifications
CAS Number
[2319790-07-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/h3r-antagonist-1-hydrochloride.html
Purity
99.10
Solubility
DMSO : 25 mg/mL (warming) |H2O : 25 mg/mL (ultrasonic)
Smiles
[H]Cl.N1(C2CCC2)CCC(CC3=NC(C4=CC=C(OCO5)C5=C4)=NO3)CC1
Molecular Formula
C19H24ClN3O3
Molecular Weight
377.87
Precautions
H302, H315, H319, H335
References & Citations
[1]WANG, Rong, et al. THERAPEUTIC USES. WO2013107336A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H3 Receptor
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MLP328 Polyclonal Antibody