VL285
Product Specifications
UNSPSC Description
VL285 is a potent VHL ligand with an IC50 of 0.34 μM[1].
Target Antigen
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/VL285.html
Purity
98.84
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@@H](N4CC(C=CC=C5)=C5C4=O)C(C)C)=O)=O)C=C2
Molecular Weight
532.65
References & Citations
[1]Buckley DL, et al. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10(8):1831-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111663/VL285-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111663/VL285-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1448188-57-5
Available Sizes
Curated Selection
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