Recombinant Mouse C-C motif chemokine 12 (Ccl12)
Product Specifications
Product Name Alternative
MCP-1-related chemokine; Monocyte chemoattractant protein 5Monocyte chemotactic protein 5 ; MCP-5Small-inducible cytokine A12
Abbreviation
Recombinant Mouse Ccl12 protein
Gene Name
Ccl12
UniProt
Q62401
Expression Region
23-104aa
Organism
Mus musculus (Mouse)
Target Sequence
GPDAVSTPVTCCYNVVKQKIHVRKLKSYRRITSSQCPREAVIFRTILDKEICADPKEKWVKNSINHLDKTSQTFILEPSCLG
Tag
N-terminal 6xHis-tagged
Type
Developed Protein
Source
E.coli
Field of Research
Others
Relevance
Chotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.
Endotoxin
Not test
Purity
Greater than 90% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Function
Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.
Molecular Weight
13.3 kDa
References & Citations
Distinct expression and function of the novel mouse chemokine monocyte chemotactic protein-5 in lung allergic inflammation.Jia G.-Q., Gonzalo J.A., Lloyd C., Kremer L., Lu L., Martinez A.C., Wershil B.K., Gutierrez-Ramos J.-C.J. Exp. Med. 184:1939-1951 (1996)
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Protein Length
Full Length of Mature Protein
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940043-100 1x 100 µL
P21 / WAF1 (WA-1), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680745-100 1x 100 µL
CD45 / LCA (2B11 + PD7/26), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682049-500 1x 500 µL
CD43 (T-Cell Marker) (SPN/2049R), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC741173-100 1x 100 µL
PTH / Parathyroid Hormone (N-Terminal) (PTH/1173), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040352-100 1x 100 µL
CD31 / PECAM-1 (158-2B3), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details