IL-17RA, Rhesus Macaque (HEK293, His)
Product Specifications
UNSPSC Description
IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F[1][2]. IL-17RA Protein, Rhesus Macaque (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 320 amino acids (M1-P320).
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/il-17ra-protein-rhesus-macaque-hek293-his.html
Purity
98.00
Smiles
LRLLDHPALV CSQPGLNCTV KNSTCLDDSW IHPRNLTPSS PKDLQIQLRF AHTQQGDLFP VAHIEWTLQT DASILYLEGA ELSVLQLNTN ERLCVKFEFL SKLRHHHKRW RFTFSHFVVD PDQEYEVTVH NLPKPIPDGD PNHQSKNFLV PDCEHTRMKV TTPCMSSGSL WDPNITVETL EAQQLRVGFT LWNESTHYQI LLTSFPHMEN HSCFEHMHHV PAPRPEDFHQ RSNVTLTLHN LKGCCRHRVQ IQPFFSSCLN DCLRHSVTVS CPEMPDTPEP IPDYMPLW
Molecular Weight
Approximately 49-75 kDa.
References & Citations
[1]Stéphane Nesmond, et al. Characteristic Pattern of IL-17RA, IL-17RB, and IL-17RC in Monocytes/Macrophages and Mast Cells From Patients With Bullous Pemphigoid. Front Immunol. 2019 Sep 11;10:2107.|[2]Xun Lin, et al. IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity. 2022 Feb 8;55(2):237-253.e8.|[3]Laura Green, et al. Chronic Candidiasis in Children. Curr Allergy Asthma Rep. 2017 May;17(5):31.
Shipping Conditions
Blue Ice
Storage Conditions
Stored at -20°C for 2 years
Available Sizes
Curated Selection
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