Recombinant Mouse WD repeat-containing and planar cell polarity effector protein fritz homolog (Wdpcp)

MSFCLTELHLWSLKSTLHIADRDIGVYQYYDKKDPSVSATEHGNLEEKQRLAESRDYPWTLKNRRPEKLRDSLKELEELMQSSPCVLSKWKSKYICQLLFGSGVLVSLSLSGPQLEKVVIDRSLVGKLISDTISDALLTDSFIILSFLAQNKLCFIQFTKKMDSLDGNKRLEKLSALDLKISYYDIPGPANRTIDRHLAVNSTQDLVVCWWPLVSDDVWPWTPVSSEKDRANMLLLGFTQGGLEVLSFVRTEWSPLDVHFGTKQPYQVFTVECSVSVDKEPMADSCIYESVRNKLHCVSVTRIPLRSKAISCCRNSTEDKLIVGCEDSSVILYEAHRGVTLLAQAELRPSLISCHPSGAILLVGSNQGELQIFDIALSPINIQLLAEDYSPKETLQFKKFFDVSSSLVQMQWMAPPVVFQKPKRGEICDLLFLRFNKGPLGVLLFKLGILTRGQLGLVDLILQYIHYSEVYEAISILRSMDWDTLGQQCLIGMGTIVNHLLRQRLTPEREAQLEASLGTFYAPTRPLLDTTILEYREPVSKYARRLFHHLLRYKRFEKAFLLAVDIGARDLFMDIHYLALDMGELALAEVARRRAHDIDVESVSSGVELLGPLDRRDMLNEGFASSALMPEGENKFPGLLPSIGSTHMQTLQQKIPNGPSSRWAIERRTEEEEEEEEEEEEELCTDSSGATTWNAEGELKEDQRKQDIGDVGSLRMVHFGLV

Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movents.

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies

Comparative transcription map of the wobbler critical region on mouse chromosome 11 and the homologous region on human chromosome 2p13-14.Fuchs S., Resch K., Thiel C., Ulbrich M., Platzer M., Jockusch H., Schmitt-John T.BMC Genet. 3:14-14 (2002)

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.