Prostaglandin B3
Product Specifications
UNSPSC Description
Prostaglandin B3 (PGB3) is a member of the class of prostaglandins B and a secondary alcohol. PGB3 exhibits a rather low affinity to human PPARγ with a Ki value greater than 1 mM compared with Ki values of 26.28 ± 8.7 μM for PGB1 and 77 ± 37.7 μM for PGB2[1].
Target Antigen
Endogenous Metabolite; PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/prostaglandin-b3.html
Solubility
10 mM in DMSO
Smiles
OC(CCC/C=C\CC1=C(CCC1=O)/C=C/[C@@H](O)C/C=C\CC)=O
Molecular Weight
332.43
References & Citations
[1]Ferry G, et al. Binding of prostaglandins to human PPARgamma: tool assessment and new natural ligands. Eur J Pharmacol. 2001 Apr 6;417(1-2):77-89.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-117431/Prostaglandin-B3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-117431/
Clinical Information
No Development Reported
CAS Number
36614-32-1
Available Sizes
Curated Selection
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