Prostaglandin B3

Prostaglandin B3 (PGB3) is a member of the class of prostaglandins B and a secondary alcohol. PGB3 exhibits a rather low affinity to human PPARγ with a Ki value greater than 1 mM compared with Ki values of 26.28 ± 8.7 μM for PGB1 and 77 ± 37.7 μM for PGB2[1].

Product Specifications

CAS Number

[36614-32-1]

Product Name Alternative

PGB3

UNSPSC

12352211

Hazard Statement

H225-H319-H336

Target

Endogenous Metabolite; PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/prostaglandin-b3.html

Solubility

10 mM in DMSO

Smiles

OC(CCC/C=C\CC1=C(CCC1=O)/C=C/[C@@H](O)C/C=C\CC)=O

Molecular Formula

C20H28O4

Molecular Weight

332.43

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Ferry G, et al. Binding of prostaglandins to human PPARgamma: tool assessment and new natural ligands. Eur J Pharmacol. 2001 Apr 6;417 (1-2) :77-89.