MR837
MR837 is an inhibitor of NSD2-PWWP1. MR837 can bind with human nuclear receptor binding SET domain protein 2 (PWWP domain) [1].
Product Specifications
CAS Number
1210906-48-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mr837.html
Purity
99.82
Solubility
DMSO : 100 mg/mL (ultrasonic) |Methanol : 125 mg/mL (ultrasonic)
Smiles
O=C(N(C1CC1)CC2=CC=CS2)C3=CC=C(C#N)C=C3
Molecular Formula
C16H14N2OS
Molecular Weight
282.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Liu Y, et, al. PWWP1 domain of NSD2 in complex with MR837.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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