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(S, S) -GSK321

(S, S) -GSK321 is a (S, S) -enantiomer of GSK321[1].

Product Specifications

CAS Number

1816272-20-4

UNSPSC

12352005

Target

Isocitrate Dehydrogenase (IDH)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-s-gsk321.html

Purity

99.78

Solubility

DMSO : 150 mg/mL (ultrasonic)

Smiles

C[C@H](O)C1=CC=CC(NC(C2=NN(C3=C2CN(C[C@@H]3C)C(C4=CC=CN4)=O)CC5=CC=C(C=C5)F)=O)=C1

Molecular Formula

C28H28FN5O3

Molecular Weight

501.55

References & Citations

[1]Okoye-Okafor UC, et al. New IDH1 mutant inhibitors for treatment of acute myeloid leukemia. Nat Chem Biol. 2015 Nov;11 (11) :878-86.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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