4-Octylphenol
4-Octylphenol is a hormone disruptor that has gender-specific effects on male reproductive cells, significantly reducing the mitotic index and the number of spermatogonia. 4-Octylphenol can cause inflammatory damage to fish gills by activating the complement system through the C3a/C3aR axis and the C5a/C5aR1 axis, this leads to complement activation and causes immune suppression due to the imbalance between Th1/Th2 cells and regulatory T cells (Treg) /Th17 cells, as well as inflammatory damage via the Toll-like receptor 7 (Toll-like Receptor (TLR) ) /IκBα/NF-κB pathway[1][2].
Product Specifications
CAS Number
1806-26-4
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Complement System; NF-κB; Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/4-octylphenol.html
Purity
98.0
Smiles
CCCCCCCCC1=CC=C(C=C1)O
Molecular Formula
C14H22O
Molecular Weight
206.32
Precautions
H315, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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