Z-FF-FMK
Z-FF-FMK is a selective cathepsin-L inhibitor. Z-FF-FMK can prevent β-amyloid to induce apoptotic changes such as activation of caspase-3, cleavage of the DNA repair enzyme, poly-ADP ribose polymerase, and DNA fragmentation[1].
Product Specifications
CAS Number
[105608-85-3]
Product Name Alternative
Z-Phe-Phe-FMK
UNSPSC
12352209
Target
Cathepsin
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/z-ff-fmk.html
Purity
98.32
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FCC([C@H](CC1=CC=CC=C1)NC([C@@H](NC(OCC2=CC=CC=C2)=O)CC3=CC=CC=C3)=O)=O
Molecular Formula
C27H27FN2O4
Molecular Weight
462.51
References & Citations
Cathepsin-L
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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