AST5902 (mesylate)
AST5902 mesylate is a principal metabolite of Alflutinib, exhibiting significant antineoplastic activity. AST5902 mesylate contributes to the overall pharmacological effects in the treatment of non-small cell lung cancer. AST5902 mesylate is involved in the response to activating EGFR mutations and can help overcome EGFR T790M drug-resistant mutations.
Product Specifications
CAS Number
2412155-75-8
UNSPSC
12352005
Target
Drug Metabolite; EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ast5902-mesylate.html
Smiles
C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OCC(F)(F)F)N=C1N(C)CCNC)=O.O=S(O)(C)=O
Molecular Formula
C28H33F3N8O5S
Molecular Weight
650.67
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![Rabbit Polyclonal GPR3 Antibody [DyLight 550]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
![Ki-67 (Proliferating Cell Marker) Recombinant Rabbit Monoclonal Antibody [Clone MKI67/4947R]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
Ki-67 (Proliferating Cell Marker) Recombinant Rabbit Monoclonal Antibody [Clone MKI67/4947R]
Ki-67 (Proliferating Cell Marker) Recombinant Rabbit Monoclonal Antibody [Clone MKI67/4947R]
Ki-67 (Proliferating Cell Marker) Recombinant Rabbit Monoclonal Antibody [Clone MKI67/4947R]
Ki-67 (Proliferating Cell Marker) Recombinant Rabbit Monoclonal Antibody [Clone MKI67/4947R]