Bizine

Bizine, a Phenelzine analogue, is a potent and selective LSD1 inhibitor, with a b>Ki of 59 nM. Bizine can modulate bulk histone methylation in cancer cells. Bizine shows neuroprotective effects[1].

Product Specifications

CAS Number

[1591932-50-1]

UNSPSC

12352005

Target

Histone Demethylase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bizine.html

Purity

96.2

Solubility

10 mM in DMSO

Smiles

NNCCC1=CC=C(NC(CCCC2=CC=CC=C2)=O)C=C1

Molecular Formula

C18H23N3O

Molecular Weight

297.39

References & Citations

[1]Prusevich P, et, al. A selective phenelzine analogue inhibitor of histone demethylase LSD1. ACS Chem Biol. 2014 Jun 20;9 (6) :1284-93.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

KDM1/LSD1

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

SR315106 1 Kit

ZFAND2B Human siRNA Oligo Duplex (Locus ID 130617)

Ask

View Details

FY13327 100 µg

BAD Antibody / Bcl2-associated agonist of cell death

Ask

View Details

RD20280F-01 25 µg

PE/Cyanine5 Anti-Mouse CD3 Antibody

Ask

View Details

RD20280F-02 100 µg

PE/Cyanine5 Anti-Mouse CD3 Antibody

Ask

View Details

NBP3-08383JF646 100 µL

Mouse Monoclonal FGF-23 Antibody (FGF23/4168) [Janelia Fluor 646]

Ask

View Details

MBS7102813 Inquire

Recombinant Drosophila melanogaster Putative odorant receptor 98a (Or98a), partial

Ask

View Details