Mal-C2-NHS ester
Mal-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[103750-03-4]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-c2-nhs-ester.html
Purity
99.30
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(ON1C(CCC1=O)=O)CCCCN2C(C=CC2=O)=O
Molecular Formula
C13H14N2O6
Molecular Weight
294.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Andrew Wood, et al. Processes for the synthesis and purification of heterobifunctional cross-linkers. WO2011023680A2.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker
Available Sizes
Curated Selection
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