What is the catalog number for CK-869?

The catalog number for CK-869 is HY-16927.

What sizes are available for CK-869?

CK-869 is available in the following size(s): 1 mg, 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does CK-869 come in?

CK-869 is available in 7 different pack sizes.

CK-869 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CK-869?

CK-869 is manufactured by QuantiMol.

What is the estimated delivery time for CK-869?

Estimated delivery time for CK-869 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CK-869?

The safety data sheet for CK-869 is available here: http://file.medchemexpress.com/batch_PDF/HY-16927/CK-869-SDS-MedChemExpress.pdf.

CK-869

CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor, with an IC50 of 7 μM.

Product Specifications

CAS Number

388592-44-7

UNSPSC

12352005

Hazard Statement

H302, H361, H372, H410

Target

Arp2/3 Complex

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/CK-869.html

Purity

99.94

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C1N(C2=CC=C(OC)C=C2OC)C(C3=CC=CC(Br)=C3)SC1

Molecular Formula

C17H16BrNO3S

Molecular Weight

394.28

Precautions

H302, H361, H372, H410

References & Citations

[1]Hetrick B, et al. Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by blocking an activating conformational change. Chem Biol. 2013 May 23;20 (5) :701-12.|[2]Yamagishi Y, et al. Use of CK-548 and CK-869 as Arp2/3 complex inhibitors directly suppresses microtubule assembly both in vitro and in vivo. Biochem Biophys Res Commun. 2018 Feb 12;496 (3) :834-839.