(R, S, S, R, S) -Boc-Dap-NE
(R, S, S, R, S) -Boc-Dap-NE is the inactive isomer of Boc-Dap-NE (HY-78931), and can be used as an experimental control. Boc-Dap-NE, is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
Product Specifications
CAS Number
[2994330-72-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Intermediate
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-s-s-r-s-boc-dap-ne.html
Purity
98.32
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1[C@H](CCC1)[C@@H](OC)[C@H](C)C(N[C@@H](C)[C@H](O)C2=CC=CC=C2)=O)OC(C)(C)C
Molecular Formula
C23H36N2O5
Molecular Weight
420.54
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Vaarhorst AA, et al. A metabolomic profile is associated with the risk of incident coronary heart disease. Am Heart J. 2014 Jul;168 (1) :45-52.e7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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