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LXR agonist 1

Product Specifications

UNSPSC Description

LXR (Liver X receptor) agonist 1 is potent LXR agonist with AC50s of 1.5 nM and 12 nM for LXR-α and LXR-β, respectively. LXR agonist 1 has the potential for the research of atherosclerosis[1].

Target Antigen

LXR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/lxr-agonist-1.html

Solubility

DMSO : 175 mg/mL (ultrasonic)

Smiles

CCC1=C(C2=CC=CC(OC3=CC(S(N(C)CCN)(=O)=O)=CC=C3)=C2)C4=CC=CC(C(F)(F)F)=C4N=C1

Molecular Weight

529.57

References & Citations

[1]Lim RK, et al. Targeted Delivery of LXR Agonist Using a Site-Specific Antibody-Drug Conjugate. Bioconjug Chem. 2015; 26(11):2216-22.

Shipping Conditions

Blue Ice

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-144549/LXR-agonist-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-144549/LXR-agonist-1-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1779524-90-1

Available Sizes

Curated Selection

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