Diethyl phosphate

Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats[1][2][3].

Product Specifications

CAS Number

[598-02-7]

Product Name Alternative

Diethyl phosphoric acid

UNSPSC

12352211

Hazard Statement

H302, H312, H314, H318

Target

Endogenous Metabolite; Interleukin Related

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/Diethyl-phosphate.html

Purity

98.08

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=P(OCC)(O)OCC

Molecular Formula

C4H11O4P

Molecular Weight

154.10

Precautions

H302, H312, H314, H318

References & Citations

[1]Kyogoku Y, et al. The crystal structure of barium diethyl phosphate[J]. Acta Crystallographica, 1966, 21 (1) : 49-57.|[2]Yang F, et al. Effects of Diethyl Phosphate, a Non-Specific Metabolite of Organophosphorus Pesticides, on Serum Lipid, Hormones, Inflammation, and Gut Microbiota. Molecules. 2019 May 24;24 (10) :2003.|[3]Yang FW, et al. Assessment of the endocrine-disrupting effects of diethyl phosphate, a nonspecific metabolite of organophosphorus pesticides, by in vivo and in silico approaches. Environ Int. 2020 Feb;135:105383.