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LY 225910

LY 225910 is a selective antagonist for cholecystokinin receptor (CCK2 receptor), which affects the excitatory response to morphine, and leads to morphine sensitization[1].

Product Specifications

CAS Number

[133040-77-4]

UNSPSC

12352005

Hazard Statement

H301, H413

Target

Cholecystokinin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ly-225910.html

Purity

98.92

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1N(C2=CC=CC(OC(C)C)=C2)C(CCC3=CNC4=C3C=C(Br)C=C4)=NC5=C1C=CC=C5

Molecular Formula

C27H24BrN3O2

Molecular Weight

502.40

Precautions

H301, H413

References & Citations

[1]Felicio LF, et al., Stimulation of either cholecystokinin receptor subtype reduces while antagonists potentiate or sensitize a morphine-induced excitatory response. Peptides. 2001 Aug;22 (8) :1299-304.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-101352/LY-225910-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-101352/LY-225910-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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