LY 225910
LY 225910 is a selective antagonist for cholecystokinin receptor (CCK2 receptor), which affects the excitatory response to morphine, and leads to morphine sensitization[1].
Product Specifications
CAS Number
[133040-77-4]
UNSPSC
12352005
Hazard Statement
H301, H413
Target
Cholecystokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly-225910.html
Purity
98.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N(C2=CC=CC(OC(C)C)=C2)C(CCC3=CNC4=C3C=C(Br)C=C4)=NC5=C1C=CC=C5
Molecular Formula
C27H24BrN3O2
Molecular Weight
502.40
Precautions
H301, H413
References & Citations
[1]Felicio LF, et al., Stimulation of either cholecystokinin receptor subtype reduces while antagonists potentiate or sensitize a morphine-induced excitatory response. Peptides. 2001 Aug;22 (8) :1299-304.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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