Propargyl-PEG6-NH2

Propargyl-PEG6-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG6-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[1198080-04-4]

UNSPSC

12352211

Hazard Statement

H302, H315, H319

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/propargyl-peg6-nh2.html

Purity

99.69

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

C#CCOCCOCCOCCOCCOCCOCCN

Molecular Formula

C15H29NO6

Molecular Weight

319.39

Precautions

H302, H315, H319

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.