MAO-A/5-HT2AR-IN-1
Product Specifications
UNSPSC Description
MAO-A/5-HT2AR-IN-1 (compound I14) is a potent MAO-A and 5-HT2AR dual inhibitor, with IC50 values of 0.004 and 0.014 μM, respectively. MAO-A/5-HT2AR-IN-1 is a potential antidepressant agent[1].
Target Antigen
5-HT Receptor; Monoamine Oxidase
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mao-a-5-ht2ar-in-1.html
Solubility
DMF : 5 mg/mL (ultrasonic;warming;heat to 80°C)|DMSO : 20 mg/mL (ultrasonic)
Smiles
O=C1C2=C(C3=NC=CC4=CC(OCCCCN5CCN(CC5)C6=C(F)C=CC=C6)=CC1=C43)C=CC=C2
Molecular Weight
481.56
References & Citations
[1]Sun X, Li N, et al. Development of MAO-A and 5-HT2AR Dual Inhibitors with Improved Antidepressant Activity. J Med Chem. 2022 Oct 13;65(19):13385-13400.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151596/MAO-A-5-HT2AR-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151596/MAO-A-5-HT2AR-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2769156-00-3
Available Sizes
Curated Selection
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