MAO-A/5-HT2AR-IN-1
MAO-A/5-HT2AR-IN-1 (compound I14) is a potent MAO-A and 5-HT2AR dual inhibitor, with IC50 values of 0.004 and 0.014 μM, respectively. MAO-A/5-HT2AR-IN-1 is a potential antidepressant agent[1].
Product Specifications
CAS Number
[2769156-00-3]
UNSPSC
12352005
Target
5-HT Receptor; Monoamine Oxidase
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mao-a-5-ht2ar-in-1.html
Purity
99.71
Solubility
DMF : 5 mg/mL (ultrasonic; warming; heat to 80°C) |DMSO : 20 mg/mL (ultrasonic)
Smiles
O=C1C2=C(C3=NC=CC4=CC(OCCCCN5CCN(CC5)C6=C(F)C=CC=C6)=CC1=C43)C=CC=C2
Molecular Formula
C30H28FN3O2
Molecular Weight
481.56
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-A; MAO-B; α-1 microglobulin
Available Sizes
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p40 phox (Neutrophil Cytosolic Factor 4, NCF4, MGC3810, NCF, NCF-4, Neutrophil cytosol factor 4, Neutrophil NADPH oxidase factor 4, P40PHOX, p40-phox, SH3 and PX domain-containing protein 4, SH3PXD4) (Biotin)
p40 phox (Neutrophil Cytosolic Factor 4, NCF4, MGC3810, NCF, NCF-4, Neutrophil cytosol factor 4, Neutrophil NADPH oxidase factor 4, P40PHOX, p40-phox, SH3 and PX domain-containing protein 4, SH3PXD4) (Biotin)
Oncofetal Antigen 5T4 (TPBG, Trophoblast Glycoprotein, 5T4 Oncofetal antigen, 5T4 Oncofetal Trophoblast Glycoprotein, M6P1) (PE)
