AZD1940

AZD1940 is an orally active, high affinity cannabinoid CB1/CB2 receptor agonist with pKi values of 7.93 and 9.06 for human CB1R and CB2R, respectively. AZD1940 shows a robust analgesia action[1][2].

Product Specifications

CAS Number

[881413-29-2]

UNSPSC

12352005

Target

Cannabinoid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/azd1940.html

Purity

99.58

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCS(=O)(NC1=CC=C2C(N=C(C(C)(C)C)N2CC3CCC(F)(F)CC3)=C1)=O

Molecular Formula

C20H29F2N3O2S

Molecular Weight

413.52

References & Citations

[1]Jarkko Kalliomäki, et al. Evaluation of the analgesic efficacy and psychoactive effects of AZD1940, a novel peripherally acting cannabinoid agonist, in human capsaicin-induced pain and hyperalgesia. Clin Exp Pharmacol Physiol. 2013 Mar;40 (3) :212-8.|[2]Magnus Schou, et al. Radiolabeling of the cannabinoid receptor agonist AZD1940 with carbon-11 and PET microdosing in non-human primate. Nucl Med Biol. 2013 Apr;40 (3) :410-4.