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EMD 57439

Product Specifications

UNSPSC Description

EMD 57439 is a selective PDE-III inhibitor. EMD 57439 does not significantly increase c-AMP concentration and has little effect on Ca(50)[1].

Target Antigen

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/emd-57439.html

Solubility

10 mM in DMSO

Smiles

O=C1S[C@H](C(C2=CC3=C(C=C2)N(CCC3)C(C4=CC=C(C(OC)=C4)OC)=O)=NN1)C

Molecular Weight

425.50

References & Citations

[1]Kusakari Y,et al. Use of the Ca-shortening curve to estimate the myofilament responsiveness to Ca2+ in tetanized rat ventricular myocytes. J Physiol Sci. 2006 Jun;56(3):219-26.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-114990/EMD-57439-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-114990/

Clinical Information

No Development Reported

CAS Number

148714-88-9

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