Metipranolol

Metipranolol is a nonselective and orally active β-adrenergic receptor antagonist. Metipranolol can be used for hypertension and glaucoma research[1][2].

Product Specifications

CAS Number

[22664-55-7]

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/metipranolol.html

Purity

98.36

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

CC(OC1=C(C=C(C(C)=C1C)OCC(CNC(C)C)O)C)=O

Molecular Formula

C17H27NO4

Molecular Weight

309.40

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Yogita Kanan, et al. Metipranolol promotes structure and function of retinal photoreceptors in the rd10 mouse model of human retinitis pigmentosa. J Neurochem. 2019 Jan;148 (2) :307-318.|[2]M F Sugrue, et al. A study on the ocular and extraocular pharmacology of metipranolol. Graefes Arch Clin Exp Ophthalmol. 1985;222 (3) :123-7.|[3]José Melena, et al. Metipranolol attenuates lipid peroxidation in rat brain: a comparative study with other antiglaucoma drugs. Graefes Arch Clin Exp Ophthalmol. 2003 Oct;241 (10) :827-33.