AMOZ

AMOZ is a carcinogenic metabolite of Furaltadone (HY-B1148A), which forms stable tissue residues by covalently binding to proteins as a hapten. AMOZ can be coupled with carrier proteins (such as BSA/OVA) to induce immune response and is released after acid hydrolysis. AMOZ residues can be detected by competitive ELISA method, and the detection limit in the monoclonal antibody 2E5.1 test is as low as 0.16 μg/kg (shrimp sample) . AMOZ can be used as a typical marker to monitor drug residues in animal-derived foods in the field of food safety[1][2].

Product Specifications

CAS Number

[43056-63-9]

Product Name Alternative

3-Amino-5-morpholinomethyl-2-oxazolidone

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/amoz.html

Concentration

10mM

Purity

99.89

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1OC(CN2CCOCC2)CN1N

Molecular Formula

C8H15N3O3

Molecular Weight

201.23

Precautions

H302, H315, H319, H335

References & Citations

[1]UmapornPimpitak, et al. Development of a monoclonal antibody-based enzyme-linked immunosorbent assay for detection of the furaltadone metabolite, AMOZ, in fortified shrimp samples. Food Chemistry. Volume 116, Issue 3, 1 October 2009, Pages 785-791.|[2]Liu YC, et al. A novel chemiluminescent ELISA for detecting furaltadone metabolite, 3-amino-5-morpholinomethyl-2-oxazolidone (AMOZ) in fish, egg, honey and shrimp samples. J Immunol Methods. 2013 Sep 30;395 (1-2) :29-36.