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PRMT5-IN-35

Product Specifications

UNSPSC Description

PRMT5-IN-35 (Compound 87) is a potent, selective and orally active PRMT5 inhibitor with an IC50 value of 1 nM . PRMT5-IN-35 can be used in cancer research[1].

Target Antigen

Histone Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/prmt5-in-35.html

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@H](O)[C@H](N2C3=NC=NC(N)=C3C=C2)O[C@@H]1[C@H](O)C4=CC=C(Cl)C=C4

Molecular Weight

376.79

References & Citations

[1]John Howard Tatlock, et al. US20160244475.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-160865/PRMT5-IN-35-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-160865/PRMT5-IN-35-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1989620-03-2

Available Sizes

Curated Selection

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